Frequently asked question: Why do children under the age of 12 with sickle cell disease take antibiotics?

Given sickle cell disease patients’ increased chance of developing serious infections due to spleen failure, children aged up to 12 are administered antibiotics twice a day in the Netherlands, generally Phenethicillin (Broxil). This is particularly important during childhood, due to the greater susceptibility to infections. Severe infections with encapsulated bacteria in particular (which are bacteria with a capsule around them, such as pneumococci, meningococci, and Hemophilus influenza) can largely be prevented by these antibiotics.

Relevant medical information