Frequently asked question: What is a radioactive iodine uptake with perchlorate discharge test?

With this scintigraphic test, perchlorate is injected via IV two hours after the injection of the iodine. After one hour, more photos are taken. These photos show whether or not the perchlorate has displaced the iodine. This only happens if the iodine cannot bind properly to the thyroid gland. If this happens, then you have an iodine organification disorder and that can cause congenital hypothyroidism, for example. Purpose: to detect disrupted uptake of iodine into the thyroid gland (iodine organification disorder).

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