Frequently asked question: Why does your immune system work less well due to the HIV infection?
Every day, billions of new virus particles are produced and billions of CD4 cells die. Special CD4 cells, the T cells, have a very important role within your immune system: they manage all the other immune cells so that each cell knows exactly what it has to do. If a large number of CD4 cells die, the other immune cells do not know what to do. Your immune system will not work properly anymore, so you can no longer defend yourself against pathogens.
Every day, billions of new virus particles are produced and billions of T cells and other CD4 cells die. The T cells have a very important role within the immune system. They control everything and manage all the other immune cells so that each cell knows exactly what it has to do. If a large number of T cells die, your immune system is no longer well managed and is unable to defend you against pathogens. You then become much more susceptible to normal, common viruses, bacteria and fungi. Eventually you can even get infections from viruses, bacteria or fungi that would not normally make you sick. These are also called opportunistic infections.